Table 1. HIV drug resistance mutations detected by standard Sanger sequencing (SS) and by Deep sequencing (DS).
| NO. | VL(COPIES/ML) | TREATMENT REGIMEN | SUBTYPE | PROTEASE (% ABUNDANCE BY DS) MUTATIONS | REVERSE TRANSCRIPTASE (% ABUNDANCE BY DS) | ||
|---|---|---|---|---|---|---|---|
| by DS only | by both SS and DS | by SS only | by DS only | ||||
| 1 | 26356 | NVP+TDF+3TC | AE | K103N (16.17%) | L74V (1.44%), V108I(15.16%), F227L(2.04) | ||
| 4 | 33645 | EFV+3TC+AZT | B | Y188C (2.45%) | |||
| 9 | 559474 | EFV+3TC+TDF | B | K103N (14.97%) | |||
| 11 | 29299 | NVP+3TC+AZT | AE | K65R (28.08%, D67N (34.53%), Y181C (98.77%), Y188H (100%) | M41L (15.99%, L74V (2.2%), T215F (12.28%), E138G(12.14%), A98G (18.52%), K103N (16.17%), V106M (15.16%), V108I (10%), G190A(50.1%), F227L (2.04%) | ||
| 12 | 75401 | EFV+3TC+AZT | AE | M184V (7.52%), T215Y (6.64%), Y188L (7.52%) | |||
| 14 | 38072 | NVP+3TC+AZT | AE | K103N (98.91%) | D67N (1.44%), V108I (1.63%), G190A (2.74%), P225H (3.92%) | ||
| 15 | 68852 | EFV+3TC+AZT | AE | M184V (26.84%), K103N (97.46%) | G190A | V75M (1.72%) | |
| 18 | 393742 | NVP+3TC+AZT | AE | M184V (91.55%), K103N (99.22%) | K70R (15.05%), V108I (16.43%), P225H (18.21%) | ||
| 19 | 440099 | NVP+3TC+AZT | C | M46L(2.68%) | |||
| 20 | 43792 | 3TC+AZT+LPV/r | AE | K103N (88.99%) | |||
| 21 | 30706 | EFV+3TC+AZT | AE | G190A (13.45%), K101E (99.18%) | V108I (17.16%) | ||
| 22 | 865605 | EFV+3TC+AZT | AE | G190E (5.09%) | |||
| 29 | 59874 | EFV+3TC+AZT | AE | Y181V (42.08%) | M184V (9.44%), Y188H (8.71%) | ||
| 30 | 370747 | NVP+3TC+AZT | AE | M184V (100%), T215F (87.97%), K103N (99.72%) | M41L (3.48%), V75M (29.92%), E138Q (2.36%) | ||
| 31 | 93200 | NVP+3TC+AZT | AE | Y181C (1.2%) | |||
| 33 | 49500 | EFV+3TC+AZT | B | K65N (6.01%), | |||
| 34 | 98000 | EFV+3TC+AZT | AE | V106A (2.43%) | |||
| 35 | 92200 | NVP+3TC+AZT | AE | V32I (14.02%) | K101E (1.65%), G190A (1.39%) | ||
Note. Stanford HIVdb algorithm≥15.