TABLE II.
Mean Ktrans in tumor volume for each animal in the control and treatment group at day 17. At this time-point, the difference between group means was the largest observed in the pilot study. The data here are used to estimate the effect size and to calculate sample size.
| Ktrans in control group (min−1) | Ktrans in treatment group (min−1) | |
|---|---|---|
| Animal 1 | 0.1805 | 0.0598 |
| Animal 2 | 0.1298 | 0.1256 |
| Animal 3 | 0.1258 | 0.0426 |
| Animal 4 | 0.1821 | 0.0884 |
| Group mean Ktrans | 0.1546 | 0.0791 |
| Std. dev | 0.0510 | |