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. 2016 Feb 19;11(2):e0149288. doi: 10.1371/journal.pone.0149288

Fig 5. mRNA levels of the pro-inflammatory cytokines.

Fig 5

Thioglycollate-elicited peritoneal macrophages from HO-1 Het mice exhibited significantly increased mRNA levels of MCP1 (A), TNF-alpha (B), IL-1-beta (C), and IL-6 (D) as measured using RT-PCR. In contrast, mRNA levels of anti-inflammatory cytokines IL-10 (E) and TGF-1 (F) were significantly lower. Moreover, YM-1 (G), one of the M2 macrophage markers, was significantly lower in HO-1 Het mice. As expected, HO-1 (H) levels were lower in HO-1 Het mice. *p<0.05, n = 3 to 5 for each group.