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GIP(3–30) and GIP(5–30) are the most potent GIP receptor antagonists. cAMP accumulation in transiently transfected COS‐7 cells with GIP receptor. (A, B) Ligand dose–response stimulated cAMP accumulation. Data shown are means ± SEM. (C, D) Dose–response curves of antagonists inhibited a constant amount of native GIP(1–42) corresponding to 50–80% of max receptor activation. Data shown are means ± SEM.
