Table 2.

Summarized molecular functions of the 22 TSGs according to the protein interaction network

Related function	False discovery rate	Number of the 22 TSGs	Other genes
Cell cycle	7.14e−12 ~ 4.48e−2	PLK2, FBW7, TP53, PTEN, APC, BRCA1, CDKN1A, CDKN2A, ING4, RASSF1, PDCD4, FADD	CUL1, CDK2, CDK4, CDKN1C, CDKN1B, GTPBP4, TP63, PHF17, BRMS1, STK4
Apoptosis	1.17e−9 ~ 1.16e−2	APC, REST, CDKN2A, FADD, ING4, TP53, Bax, BRCA1	BRMS1, TP63, FAS, STK4, CDKN1B, BCL2, CUL1
Protein ubiquitination	4.97e−9 ~ 4.39e−2	BRCA1, FBW7, TP53, CDKN2A, RASSF1, PTEN	BTRC, CUL1, DAXX, GTPBP4, CDK2
Cell growth	1.29e−8 ~ 4.25e−5	PTEN, ING4, TP53, CDKN1A, CDKN2A, ING1, HIN-1	CDKN1B, PHF17, BCL-2, BRMS1