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. 2016 Feb 19;7:33. doi: 10.1186/s13287-016-0288-1

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© Chen et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The flow chart of the trial describes the selection, randomization, treatment and follow-up process. A physician (Investigator 3) performed the follow-up examination of the patients and remained blinded to the treatment conditions until the clinical trial was completed. GTR Guided tissue regeneration