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. Author manuscript; available in PMC: 2016 Apr 10.
Published in final edited form as: Crit Rev Biochem Mol Biol. 2015 Apr 10;50(2):134–141. doi: 10.3109/10409238.2015.1016215

Figure 5. SEPs subcellular localization and their involvement in protein-protein interaction.

Figure 5

SEPs are expressed at various subcellular locations such as in the nucleus, mitochondria, as well as the cytosol, suggesting that SEPs can have molecular activities in the cell. In one example (Slavoff et al.), a SEP participates in protein-protein interaction with Ku70/Ku80 complex and plays a regulatory role in the DNA non-homologous end joining (NHEJ) repair process.