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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Exp Neurol. 2016 Jan 11;277:215–226. doi: 10.1016/j.expneurol.2016.01.004

Fig. 2. LFPI decreases lateral amygdala evoked basolateral amygdala fEPSP's.

Fig. 2

(A) Representative fEPSP recordings from brain slices of sham (green) and LFPI (red) animals (200 μA stimulation intensity). (B) Average fEPSP slope input-output (I/O) curve (50-500 μA, 50 μA steps, stimulation). LFPI causes a significant decrease in the BLA I/O curve (sham n=16 slices / 10 animals, LFPI n=14 slices / 7animals, P <0.001***). Black line denotes repeated measures that are significantly different in post hoc comparisons. (C) Distribution of fEPSP slopes recorded simultaneously with VSD imaging experiments (200 μA stimulation). LFPI causes a significant decrease in the BLA fEPSP slope (sham n=17 slices / 10 animals, LFPI n=14 slices / 7animals, P <0.002**). (D) BLA fEPSP amplitude paired pulse ratio (200 μA stimulation, 70 ms inter stimulus interval). LFPI has no effect on BLA fEPSP paired puse ratio (sham n=14 slices / 8animals, LFPI n=12 slices / 7 animals, P= 0.999). (Experimental set-up) Representative brain slice showing amygdala subregions and electrode placements. “Stim” and “Record” arrows show placement of tip of stimulation and recording electrodes.