Table 1. Demographic and Cognitive Test Performance by Case Status.
| Controls (n = 17) | SCD Patients (n = 31) | |||
|---|---|---|---|---|
|
|
|
|||
| Variable | Mean (SD) | mean (SD) | Diff | P value |
| Age | 36.71 (11.52) | 33.32 (11.07) | 0.323 | |
| Female, freq. (%) | 9 (52.9) | 16 (51.6) | 0.930 | |
| Education (yrs) | 16.12 (1.45) | 14.13 (1.45) | <.001 | |
| Depression | 5.62 (6.05) | 6.39 (6.88) | 0.710 | |
| MMSE | 30.13 (2.45) | 29.35 (0.95) | 0.128 | |
| CNS Vitals Signs Scores* | ||||
| Full Index | 89.76 (13.40) | 84.03 (15.11) | 5.73 | 0.451 |
| Memory | 86.65 (19.34) | 85.61 (21.63) | 1.04 | 0.940 |
| Executive Functioning | 89.82 (23.64) | 83.29 (21.55) | 6.53 | 0.951 |
| Attention | 91.47 (24.46) | 86.68 (23.55) | 4.79 | 0.961 |
| Processing Speed | 95.09 (10.37) | 84.32 (10.21) | 10.77 | 0.019 |
| Processing Speed-adjusted Full Index | 84.08 (15.66) | 87.21 (14.01) | -3.13 | 0.538 |
Two sample t-tests were used to determine group differences on age, education, depression and MMSE scores; chi-square analysis tested group differences on gender.
*
Mean and SD are based on age-normed standard scores; P values are based on multivariable ANOVA models adjusted for age and education level; MMSE = Mini-Mental Status Exam