Table 2. Clustering of SPADE Symptoms above Threshold (T-score ≥ 55)*.
| Pain (n = 202) |
Fatigue (n = 164) |
Sleep (n = 132) |
Anxiety (n = 93) |
Depression (n = 79) |
|
|---|---|---|---|---|---|
| Pain, n (%) | 148 (90.2) | 122 (92.4) | 86 (92.5) | 75 (94.9) | |
| Fatigue, n (%) | 148 (73.3) | 113 (85.6) | 83 (89.3) | 73 (92.4) | |
| Sleep, n (%) | 122 (60.4) | 113 (68.9) | 66 (71.0) | 57 (72.2) | |
| Anxiety, n (%) | 86 (42.6) | 83 (50.6) | 66 (50.0) | 71 (89.9) | |
| Depression, n (%) | 75 (37.1) | 73 (44.5) | 57 (43.2) | 71 (76.3) | |
| No. Comorbid Symptoms, n (%) | |||||
| 0 | 22 (10.9) | 17 (10.4) | 17 (12.9) | 9 (9.7) | 6 (7.6) |
| 1 | 51 (25.3) | 36 (22.0) | 28 (21.2) | 21 (22.6) | 16 (20.3) |
| 2 | 57 (28.2) | 48 (29.3) | 35 (26.5) | 27 (29.0) | 22 (27.9) |
| 3 | 44 (21.8) | 37 (22.6) | 35 (26.5) | 20 (21.5) | 20 (25.3) |
| 4 | 28 (13.9) | 26 (15.9) | 17 (12.9) | 16 (17.2) | 15 (19.0) |
*
Each symptom group is represented in a column and the totals of all 5 symptom groups exceeds 250 because of high co-occurrence rates. Proportions should be read down each column. For example, of the 202 patients with threshold-level pain, the proportion with fatigue, sleep, anxiety, and depression is 73.3%, 60.4%, 42.6%, and 37.1%, respectively. Likewise, the proportion with pain only, or 1, 2, 3, or 4 additional comorbid symptoms is 10.9%, 25.3%, 28.2%, 21.8%, and 13.9%, respectively.