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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Exp Neurol. 2015 Dec 11;277:1–9. doi: 10.1016/j.expneurol.2015.12.003

FIGURE 2. Bexarotene treatment increases the levels of ABCA1 and apoE, but not LRP1, in the cortex of aged mice.

FIGURE 2

A. The levels of ABCA1 in the cortex of old control and nLrp1−/− mice (male, 20-24 months) with or without bexarotene treatment (100 mg/kg/day) for 8 weeks were analyzed by Western blotting. B, C. The levels of apoE in the cortex were detected by Western blotting (B) and ELISA (C). D. LRP1 level was analyzed in the cortex from the above described mice by ELISA (N=4-6/group). Data are plotted as mean ± SEM. *p<0.05, **p<0.01 by Tukey’s post-hoc analysis of two-way ANOVA. n.s., not significant.