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. 2016 Feb 7;2016:9154230. doi: 10.1155/2016/9154230

Figure 2.

Figure 2

Effects of UCP2 on LPS-induced inflammatory lung injury, pulmonary edema, and survival rate. Mice were pretreated with UCP2-Ad, control virus (UCP2-NC), or genipin following injected LPS or saline. (a) Lungs from each group were processed for histological examination after H&E staining (400x). (b) Lung injury score in each group (n = 5). (c) The W/D ratio (n = 5). (d) Total protein concentrations in BALF. (e) Total cells number in BALF. (f) The levels of TNF-α, IL-1β, and IL-6 in the BALF were quantified by ELISA (n = 5). (g) The comparisons of survival rate in each group (n = 16). ∗ P < 0.05 versus UCP2-NC + saline group, # P < 0.05 versus UCP2-NC + LPS group, and + P < 0.05 versus the UCP2-Ad + LPS group. Values are presented as means ± SEM.