Table 4.

Multivariate Analyses (linear mixed models) of smoking cessation and changes in plasma total glutathione and total cysteine (all baseline smokers)

	tGSH [μM]		tCys [μM]
	β	95% CL, P-value	β	95% CL, P-value
	Model 1
Smoking status
Continuing smoker	Ref.		Ref.
Quitter	0.45	(0.14; 0.76), 0.004	7.4	(−14.7; 29.6), 0.51
N		411		412
	Model 2
Smoking status
Continuing smoker	Ref.		Ref.
Quitter	0.58	(0.23; 0.93), 0.001	9.2	(−16.5; 34.8), 0.48
N		347		349

Model 1: Adjusted for age, sex, education, baseline-level of respective parameter (=correction for autocorrelation), and clustering of patients by general practitioner (random effect)

Model 2: like Model 1, but additionally adjusted for baseline level of and change in BMI, and baseline history of diseases (coronary heart disease, diabetes, hypertension, cancer)