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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Immunol. 2016 Feb 1;196(5):2249–2261. doi: 10.4049/jimmunol.1401545

Figure 5.

Figure 5

Dectin-1 dependent Syk activation is required for TLR9 recruitment to β-1,3 glucan and fungal phagosomes. (A-D) Confocal microscopy of Dectin-1-knockout macrophages expressing TLR9-mCherry and GFP-Dectin-1 or GFP-Dectin-1ΔY15 incubated with β-1,3 glucan beads for 3 h (A and B), CpG+IgG beads for 2h (C and D), heat-killed A. fumigatus (E and F), or heat-killed C. albicans (G and H). Original magnification X60 and X100. Scale bar indicates 5µm. Data are representative of five independent experiments.