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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: J Immunol. 2016 Feb 1;196(5):2249–2261. doi: 10.4049/jimmunol.1401545

Figure 6.

Figure 6

Dectin-1 regulates TLR9 dependent gene expression. (A–B) Microarray data analysis of TLR9KO and wild-type B6 immortalized macrophages in response to β-1,3 glucan beads. (A) A scatter plot indicating a ratio of fold changes in gene expression between wild-type and TLR9KO macrophages. Off-diagonal dots (red) indicate differentially regulated TLR9 dependent genes that are fold change > 2.0 between macrophages stimulated with β-1,3 glucan beads and unstimulated. (B) A heat map of the 32 genes differentially expressed (fold change > 1.8) between TLR9KO and wild-type macrophages in response to β-1, 3 glucan beads.