Percentages of positive specimens in oral fluid (OF) at different confirmatory cutoffs for 10 participants after 25 mg controlled intravenous cocaine administration. Cutoffs evaluated were: cocaine ≥ 1 μg/L, benzoylecgonine (BE) ≥ 1 μg/L, cocaine ≥ 8 μg/L (SAMHSA), BE ≥ 8 μg/L (SAMHSA), cocaine ≥ 10 μg/L (DRUID), and BE ≥ 10 μg/L (DRUID). Note that not all oral fluid collection time points were n= 10 as different cocaine dosing days had different oral fluid collection times beyond 21 h: four Oral-Eze (OE) and three StatSure (SS) OF specimens were collected at 28 h; three OE and four SS OF specimens at 33 h; and six OE and seven SS OF specimens at 45 and 69 h.