Fig. 5.
Flow cytometry analysis of tumor-infiltrating immune cells. Flow cytometry of tumors excised on treatment day 12 (Fig. 2) were analyzed for increases in the indicated tumor-infiltrating immune cells by flow cytometry using the indicated immune cell markers. Data comparing untreated and CPA-treated tumors are shown in Appendix S1, and representative flow cytometry gating images are shown in Appendix S1. Significance for comparisons to untreated tumors is indicated by: *p < 0.05; **p < 0.01; ***p < 0.001; and ****p < 0.0001. Combination treatment groups were compared to CpG-1826 alone (dagger symbol) or CPA (double dagger) by two-tailed t-test, p < 0.05.