Figure 8. Modification of platelet proteins by A-HNE.
Platelets were incubated with either media or AHNE (30 µM) for 1h, after which Click Chemistry was performed and the biotinylated proteins were pulled down with NeutrAvidin beads. The lysates were separated using SDS-PAGE gel and (B) western blot for streptavidin and (B) western blot for actin, citrate synthase and ATP synthase subunit α were performed. Data from an individual platelet donor.