Fig. 2.

BOLD response for the 2back > 0back contrast in healthy controls and fibromyalgia patients.

Both groups demonstrated increased fMRI activations in 2back > 0back in a widespread fronto-parietal network of brain regions typically activated in working memory tasks, including bilateral DLPFC, VLPFC, parietal cortices, precuneus, SMA, ACC, and insula (p < 0.05 cluster-corrected). Controls n = 13, red; patients n = 15, blue. Colorbars are t-values from 2.5 to 5. (For interpretation of the references to color in this figure, the reader is referred to the online version of this chapter.)