Table 3.

Positive association between NBack-related BOLD response and task accuracy during the 2back task.

Region	Peak t-value	Peak MNI coordinate	Cluster volume (voxels)	Cluster p-value
Controls (n = 12):
aINS (R), FrOP (R), Putamen (R)	4.4	32, 22, 8	1447	0.004
Putamen (L), Caudate (L)	4.2	− 24, 6, 6	584	0.047
PMC (R), DLPFC (R)	3.5	32, − 2, 32	629	0.040
Patients (n = 15):
No significant clusters
Controls > patients:
aINS (R)	3.7	32, 22, 8	648	0.038
Patients > controls:
No significant clusters

The threshold for these analyses was set at a voxel-wise p < 0.01. Significant clusters corrected for multiple comparisons at p < 0.05 using random field theory (RFT) are reported. Included in these analyses were n = 12 controls (performance data missing for one subject) and n = 15 patients.

aINS, anterior insula; FrOP, frontal operculum; PMC, premotor cortex; DLPFC, dorsolateral prefrontal cortex; L, left hemisphere; R, right hemisphere.