Table 1.
MAF | HWE | 95% CI | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
SNP | A1/A 2 | CHR | Case | Control | p | OR | Lower | Upper | p | |
1 | rs10430146 | G/A | 1 | 0.32 | 0.05 | 0.20 | 12.50 | 4.79 | 32.61 | 0.0001 |
2 | rs905965 | G/A | 2 | 0.51 | 0.17 | 0.45 | 6.17 | 2.87 | 13.28 | 0.0001 |
3 | rs376511 | A/G | 3 | 0.46 | 0.07 | 1.00 | 24.40 | 8.68 | 68.62 | 0.0001 |
4 | rs12629897 | T/C | 3 | 0.70 | 0.27 | 0.59 | 7.12 | 3.29 | 15.41 | 0.0001 |
5 | rs13086279 | G/A | 3 | 0.44 | 0.10 | 0.15 | 6.66 | 3.08 | 14.38 | 0.0001 |
6 | rs1846594 | G/A | 3 | 0.65 | 0.20 | 0.51 | 13.80 | 4.96 | 38.42 | 0.0001 |
7 | rs7632505 | G/A | 3 | 0.73 | 0.20 | 0.50 | 29.47 | 7.16 | 121.30 | 0.0001 |
8 | rs891666 | A/T | 3 | 0.43 | 0.11 | 0.59 | 7.26 | 3.22 | 16.35 | 0.0001 |
9 | rs2700474 | C/G | 3 | 0.43 | 0.12 | 0.60 | 7.48 | 3.24 | 17.25 | 0.0001 |
10 | rs4266183 | G/A | 3 | 0.43 | 0.11 | 1.00 | 14.06 | 5.34 | 37.03 | 0.0001 |
11 | rs831781 | G/C | 5 | 0.64 | 0.25 | 0.57 | 6.32 | 2.97 | 13.46 | 0.0001 |
12 | rs331047 | G/A | 5 | 0.63 | 0.25 | 0.57 | 6.11 | 2.87 | 13.02 | 0.0001 |
13 | rs6929018 | T/C | 6 | 0.54 | 0.18 | 0.72 | 7.69 | 3.33 | 17.76 | 0.0001 |
14 | rs494238 | G/A | 6 | 0.51 | 0.15 | 0.68 | 6.28 | 2.98 | 13.23 | 0.0001 |
15 | rs1859604 | T/G | 7 | 0.37 | 0.07 | 1.00 | 8.66 | 3.58 | 20.92 | 0.0001 |
16 | rs10178082 | T/A | 7 | 0.79 | 0.16 | 1.00 | 18.09 | 6.56 | 49.92 | 0.0001 |
17 | rs7863803 | A/G | 9 | 0.34 | 0.07 | 1.00 | 12.01 | 4.70 | 30.70 | 0.0001 |
18 | rs2456672 | C/T | 10 | 0.63 | 0.26 | 1.00 | 8.67 | 3.41 | 22.02 | 0.0001 |
19 | rs2851117 | T/T | 11 | 0.11 | 0.63 | 0.48 | 0.08 | 0.03 | 0.21 | 0.0001 |
20 | rs7248 | A/C | 12 | 0.39 | 0.05 | 1.00 | 10.21 | 4.05 | 25.71 | 0.0001 |
21 | rs11110833 | G/A | 12 | 0.56 | 0.20 | 0.51 | 8.47 | 3.50 | 20.49 | 0.0001 |
22 | rs9528951 | C/T | 13 | 0.47 | 0.14 | 0.34 | 6.73 | 3.05 | 14.84 | 0.0001 |
23 | rs9550256 | A/T | 13 | 0.65 | 0.22 | 1.00 | 6.29 | 3.09 | 12.80 | 0.0001 |
24 | rs8017647 | T/C | 14 | 0.41 | 0.08 | 0.39 | 7.90 | 3.43 | 18.22 | 0.0001 |
25 | rs8072266 | C/T | 17 | 0.36 | 0.09 | 1.00 | 10.08 | 4.11 | 24.70 | 0.0001 |
26 | rs1006644 | A/G | 20 | 0.64 | 0.18 | 0.72 | 6.15 | 3.12 | 12.12 | 0.0001 |
SNP, single-nucleotide polymorphism; A1/A2, tested allele (minor allele by default); CHR, chromosome; OR, odds ratio; 95% CI lower, lower bound of 95% confidence interval for odds ratio; 95% CI upper, upper bound of 95% confidence interval for odds ratio; STAT, coefficient Wald statistic; HWE, Hardy–Weinberg equilibrium; HWEp, p-value for H–W; p, asymptotic p-value for Wald statistic.