Skip to main content
Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1976 Sep;29(9):788–794. doi: 10.1136/jcp.29.9.788

A case of veno-occlusive disease of the liver in Britain associated with herbal tea consumption.

J McGee, R S Patrick, C B Wood, L H Blumgart
PMCID: PMC476180  PMID: 977780

Abstract

Veno-occlusive disease of the liver with clinical and pathological features similar to those of the condition occurring in the Caribbean is described in a young woman resident in Britain. The diagnosis was made from liver biopsies and hepatic venography and was confirmed at necropsy. Small amounts of pyrroliziding alkaloids were recovered from a sample of mate (Paraguay) tea, owned by the patient, to which she was addicted. It seems probable that the consumption of large amounts of this tea over a period of years was the cause of the hepatic disease.

Full text

PDF
793

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen J. R., Carstens L. A., Katagiri G. J. Hepatic veins of monkeys with veno-occlusive disease. Sequential ultrastructural changes. Arch Pathol. 1969 Mar;87(3):279–289. [PubMed] [Google Scholar]
  2. BRAS G., JELLIFFE D. B., STUART K. L. Veno-occlusive disease of liver with nonportal type of cirrhosis, occurring in Jamaica. AMA Arch Pathol. 1954 Apr;57(4):285–300. [PubMed] [Google Scholar]
  3. Ecker J. A., McKittrick J. E., Failing R. M. Thrombosis of the hepatic veins. "The Budd-Chiari syndrome"--a possible link between oral contraceptives and thrombosis formation. Am J Gastroenterol. 1966 Jun;45(6):429–443. [PubMed] [Google Scholar]
  4. Hoyumpa A. M., Jr, Schiff L., Helfman E. L. Budd-Chiari syndrome in women taking oral contraceptives. Am J Med. 1971 Jan;50(1):137–140. doi: 10.1016/0002-9343(71)90213-0. [DOI] [PubMed] [Google Scholar]
  5. Knox F. G., Schneider E. G., Willis L. R., Strandhoy J. W., Ott C. E., Cuche J. L., Goldsmith R. S., Arnaud C. D. Proximal tubule reabsorption after hyperoncotic albumin infusion. Role of parathyroid hormone and dissociation from plasma volume. J Clin Invest. 1974 Feb;53(2):501–507. doi: 10.1172/JCI107583. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Lidberg L. An experimental study of veno-occlusive disease (endophlebitis hepatica obliterans). Acta Soc Med Ups. 1966;71(5):263–280. [PubMed] [Google Scholar]
  7. MCLEAN E., BRAS G., GYOERGY P. VENO-OCCLUSIVE LESIONS IN LIVERS OF RATS FED CROTALARIA FULVA. Br J Exp Pathol. 1964 Jun;45:242–247. [PMC free article] [PubMed] [Google Scholar]
  8. PARKER R. G. Occlusion of the hepatic veins in man. Medicine (Baltimore) 1959 Dec;38:369–402. doi: 10.1097/00005792-195912000-00002. [DOI] [PubMed] [Google Scholar]
  9. Reed G. B., Jr, Cox A. J., Jr The human liver after radiation injury. A form of veno-occlusive disease. Am J Pathol. 1966 Apr;48(4):597–611. [PMC free article] [PubMed] [Google Scholar]
  10. STEIN H., ISAACSON C. Veno-occlusive disease of the liver. Br Med J. 1962 Feb 10;1(5275):372–374. doi: 10.1136/bmj.1.5275.372. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Sterup K., Mosbech J. Budd-Chiari syndrome after taking oral contraceptives. Br Med J. 1967 Dec 16;4(5580):660–660. doi: 10.1136/bmj.4.5580.660. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group

RESOURCES