Table 1.
Physiological Parameters in Isoflurane-Anesthetized Naive Rats
| Baseline | 2.5 h | 5 h | 7 h | 9 h | |
|---|---|---|---|---|---|
| MABP (mmHg) | 90.5 ± 0.9 | 87.4 ± 3.7 | 95.1 ± 3.7 | 95.6 ± 9.4 | 99.2 ± 11.1 |
| rCBF (flux) | 323.2 ± 60.8 | 328.9 ± 69.4 | 317.7 ± 61.5 | 305.5 ± 47.8 | 281.6 ± 52.5 |
| pH | 7.41 ± 0.02 | 7.42 ± 0.01 | 7.42 ± 0.01 | 7.43 ± 0.01 | 7.43 ± 0.01 |
| PaCO2 | 44.0 ± 0.91 | 41.0 ± 1.82 | 40.5 ± 1.32 | 38.5 ± 1.25 | 37.3 ± 1.31 |
| PaO2 (mmHg) | 110.2 ± 9.8 | 102.0 ± 10.8 | 105.8 ± 0.4 | 106.5 ± 1.4 | 104.1 ± 10.4 |
Data are expressed as mean ± SEM; n = 4.
MABP, mean arterial blood pressure; PaCO2, partial pressure of carbon dioxide; PaO2, partial pressure of oxygen; rCBF, regional cerebral blood flow.