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Relationship between 5-FC/5-FU sensitivity and relative mRNA expression of 5-FU metabolic genes. Heatmap representation of the relative mRNA expression of seven factors involved in 5-FU nucleotide metabolism across nine human cell lines. The cell lines are ordered from left to right by 5-FC LD50 in Toca 511-infected cells, starting with the lowest LD50. The Pearson correlation compares relative mRNA expression to log10[LD50].
