Table 6:
Recanalization in Included RCTs
| Author, Year | Intervention | Control | Effect Variable | Unadjusted Value (95% CI) | Adjusted Value (95% CI) |
|---|---|---|---|---|---|
| Berkhemer et al, 201527 | 141/187 (75.4)a | 68/207 (32.9)a | Odds ratio | 6.27 (4.03–9.74) | 6.88 (4.34–10.94) |
| Campbell et al, 201528 | 33 (94)b | 15 (43)b | Odds ratio | 22.0 (4.5–106.0)c | 29.0 (5.4–155.0)c |
| Goyal et al, 201529 | NR | 43/138 (31.2)d: 41/110 (37.3) with IVT 2/28 (7) without IVT |
NR | NR | NR |
Abbreviations: AOL, Arterial Occlusive Lesion; CI, confidence interval; IVT, intravenous thrombolysis; NR, not reported; RCT, randomized controlled trial; TIMI, Thrombolysis in Myocardial Infarction.
Measured as number of patients with no intracranial occlusion on follow-up CT angiography: number/total number (%). Data for follow-up computed tomography angiography were not available for 106 patients, owing to imminent death or death (24 patients), decreased kidney function (13 patients), insufficient scan quality (5 patients), and other reasons (64 patients).
Recanalization was defined as a TIMI score of 2 or 3 (partial or complete restoration of flow at the site of arterial occlusion) and measured at 24 hours. This analysis was adjusted for the site of vessel occlusion at baseline.
P < 0.001.
Recanalization was measured by a modified AOL score. A score of 2 or 3 indicates partial or complete recanalization: number/total number (%).