Table 2. The top 50 molecules in order of statistical power for building ESCC-related classifiers.
| Approaches | Top 50 molecules | |||
|---|---|---|---|---|
| SDNs | ||||
| GRB2 | FN1 | MAPK1 | CTNNB1 | YWHAG |
| YWHAZ | ACTB | EEF1A1 | UBC | STAT3 |
| YWHAE | ALB | YWHAB | PPP2R1A | RPS3 |
| ITGB | SYK | CAV1 | STAT1 | DDB1 |
| EEF1G | RUVBL2 | YBX1 | YWHAH | RBM8A |
| RUVBL1 | KPNB1 | RPS6 | FLNA | RPL3 |
| HNRNPA1 | RPS8 | PSMD2 | ACTN1 | RPS15A |
| HNRNPU | SF3B3 | KHDRBS1 | HNRNPM | RPL12 |
| RPL18 | RPLP2 | RPS17 | RPS2 | RPL7 |
| RPS18 | RPS28 | EIF2S1 | RPSA | RPL10 |
| DEPs | ||||
| DDOST | HTATSF1 | TFRC | RPS15A | KRT17 |
| PPP2R1A | SH3BGRL | MCM4 | RPLP2 | VCAN |
| PKP3 | AKR1A1 | CYB5R3 | PSMA5 | LAMP2 |
| S100A11 | CCT5 | RPSA | PSMC1 | SERPINH1 |
| ARL8B | CTSB | EFHD2 | TAGLN2 | NNMT |
| CRNN | CSTB | FLG | TGM3 | SPINK5 |
| RALY | SELENBP1 | ZNF185 | SPRR3 | A2ML1 |
| TGM1 | CRABP2 | IL1RN | AQP1 | SPRR1A |
| MUC5B | MYLK | TPM2 | GRHPR | AKAP12 |
| CSTA | YAP1 | TXN | SLC9A3R1 | IVL |
| DEGs | ||||
| RFC4 | CBX3 | ECT2 | COL1A1 | MMP1 |
| MFAP2 | KIF4A | CKS1B | SPP1 | MCM6 |
| MCM2 | PLAU | AGRN | BUB1B | KIF14 |
| GINS1 | BID | CDK1 | NUP155 | ATP2C1 |
| CEP55 | PDIA6 | SNAI2 | ACLY | ITPR3 |
| PLXNA1 | ACTL6A | FSCN1 | RPN1 | UBE2C |
| KIF2C | DLGAP5 | SOX4 | CENPF | PTK7 |
| RANBP1 | DNMT1 | NUDT1 | COL7A1 | DTL |
| CDH11 | FANCI | KIF20A | RUVBL1 | ATR |
| MEST | FZD6 | CENPA | EFNA1 | CRYL1 |
Note: Underlined and bold molecules denotes overlaps between SDNs and DEPs, SDNs and DEGs, respectively.