Table 2. Behavioral performance during auditory “oddball” task: Mean ± SD.
| Memantine | Placebo | |||||
|---|---|---|---|---|---|---|
| Baseline | 1-year | Δ | Baseline | 1-year | Δ | |
| RT (ms) | 503 ± 90 | 505 ± 82 | 2.1 ms | 500 ± 79 | 524 ± 91 | 24 ms |
| Accuracy % | 95.2 ± 11.7 | 96.6 ± 7.5 | 1.4% | 96.3 ± 4.7 | 94.8 ± 9.8 | −1.5% |
| |Count-Hit| | 2.52 ± 2.95 | 1.27 ± 1.79 | −1.24 | 1.43 ± 1.14 | 2.07 ± 2.39 | 0.65 |
| d' | 6.02 ± 1.86 | 6.72 ± 2.35 | 0.70 | 5.79 ± 2.03 | 5.64 ± 1.97 | −0.15 |
Abbreviations: 1-year = 1-year follow-up; RT = response time; Δ = 1-year − baseline; d′ = d-prime, the sensitivity measure in signal detection theory, calculated by subtracting the normalized values of the false alarm rates from that of the hit rates.