Table 6.
Clinical trial enrollment decisions across clinical scenario and time window including perfusion imaging selections using CT or MRI
Clinical scenario #1: M1 occlusion, small infarct, large penumbra | Clinical scenario #1: ICA occlusion, small infarct, large penumbra | Clinical scenario #1: M1 occlusion, large infarct, no penumbra | Clinical scenario #2: M1 occlusion, small infarct, small penumbra | Clinical scenario #3: M1 occlusion, small infarct, small penumbra | Clinical scenario #3: M2 occlusion, small infarct, small penumbra | Clinical scenario #3: No occlusion, small infarct, normal perfusion | Clinical scenario #4: Basilar occlusion | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
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Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | Yes | No | |
0–3 h | 76% (76) | 24% (24) | 67% (68) | 33% (34) | 33% (33) | 67% (67) | 58% (61) | 42% (44) | 58% (46) | 42% (33) | 39% (31) | 61% (49) | 5% (4) | 95% (74) | 48% (46) | 52% (49) |
6 h | 78% (102) | 22% (29) | 72% (93) | 28% (37) | 27% (36) | 73% (95) | 59% (74) | 41% (51) | 61% (62) | 39% (39) | 45% (45) | 55% (56) | Scenario not surveyed at this time window | 50% (63) | 50% (63) | |
6-h post ET | 48% (32) | 52% (34) | 48% (32) | 52% (35) | 32% (22) | 68% (47) | 59% (41) | 41% (29) | 54% (33) | 46% (28) | 63% (40) | 37% (23) | Scenario not surveyed at this time window | 49% (34) | 51% (36) | |
10 h | 65% (59) | 35% (32) | Scenario not surveyed at this time window | Scenario not surveyed at this time window | Scenario not surveyed at this time window | 51% (40) | 49% (38) | Scenario not surveyed at this time window | Scenario not surveyed at this time window | 49% (44) | 51% (45) | |||||
Wake-up | 79% (107) | 21% (28) | Scenario not surveyed at this time window | Scenario not surveyed at this time window | Scenario not surveyed at this time window | 60% (67) | 40% (44) | Scenario not surveyed at this time window | Scenario not surveyed at this time window | 53% (70) | 47% (61) |
CT: Computed Tomography; MRI: Magnetic Resonance Imaging.