Table 5.
Age of onset of symptoms in years from SBRS ratings by parents.
| MPS IIIB (N = 10) |
MPS IIIBa (N = 8) |
MPS IIIA (N = 8)b |
||||
|---|---|---|---|---|---|---|
| Mean (SD) age of onset | Mean (SD) age of onset | Mean (SD) age of onset | ||||
| Movement cluster | 8.22 | (6.97) | 4.67 | (2.03) | 4.14 | (3.00) |
| Social-emotional cluster | 8.69 | (8.12) | 4.33 | (2.63) | 4.62 | (3.19) |
| Lack of fear cluster | 5.60 | (4.46) | 3.66 | (1.73) | 3.90 | (2.52) |
| Executive function cluster | 5.26 | (4.05) | 3.89 | (2.26) | 4.56 | (2.97) |
| Domains: | ||||||
| Mood, anger and aggression | 6.40 | (5.17) | 4.38 | (1.36) | 5.78 | (4.08) |
| Orality | 10.64 | (10.11) | 5.08 | (3.65) | 6.43 | (6.38) |
| Mean across all areas | 7.47 | (6.48) | 4.33 | (2.28) | 4.91 | 3.69 |
9.3% of missing values for age of onset in MPS IIIB and 21.2% missing values for MPS IIIA.
a
Designates group with outliers (older patients) removed.
b
Sample size is 8 due to one patient missing SBRS.