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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Mol Cancer Ther. 2015 Sep 16;14(12):2901–2908. doi: 10.1158/1535-7163.MCT-15-0217

Figure 3. IR exposure acutely decreases tumor lactate levels.

Figure 3

A) Bilateral flank tumors were created simultaneously. Tumors were allowed to grow. One set of tumors (n=4) was maintained as a control and the other set of tumors (n=4) irradiated to a total dose of 5 Gy. Immediately following irradiation, tumors were harvested. Tissue levels of lactate were measured and normalized to total protein content. Top panel illustrates paired tumor data, while bottom panel illustrates average data from control and irradiated tumor groups. B) Control (n=5) and irradiated (n=5; 5 Gy) orthotopic xenograft tumors were harvested immediately post-irradiation. Tissue levels of lactate were measured and normalized to total protein levels.