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. Author manuscript; available in PMC: 2016 Feb 22.
Published in final edited form as: J Alzheimers Dis. 2009;18(1):211–230. doi: 10.3233/JAD-2009-1138

Fig. 4. Lifespan profile of AD related proteins (AβPP, SP1, and Aβ) in the primate brain.

Fig. 4

Protein from cortical tissue of Cynomolgus primate was isolated and probed with 22C11 AβPP N–terminus antibody with SDS–PAGE western blot analysis as described in the text. The SP1 antibody used is mentioned in the methods section. Protein was also used to measure Beta amyloid (Aβ) 1–40 using an ELISA assay (IBL, Japan). A) Relative AβPP protein signal; B) Relative SP1 signal; C. Aβ40 levels. Each data point in the curve is the mean + SEM (n=3 monkeys). Western blot results were normalized to β–actin signal.