Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 15;30(4):399–407. doi: 10.1101/gad.274134.115

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Santanam et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

Figure 5. — Autophagy ablation delays progression of castrate-resistant prostate cancer. (A) Representative Atg7 and p62 IHC of anterior prostate tissue from castrated Atg7^+/+ and Atg7^Δ/Δ mice. (B) Representative gross anatomy of urogenital systems of mice with Atg7^+/+ and Atg7^Δ/Δ prostates at 2 and 17 wk PC. (C) Prostate weights as percent body weights from castrated mice. (D) Representative histology of H&E-stained sections of Atg7^+/+ and Atg7^Δ/Δ prostates at 2 and 17 wk PC. (E) Magnetic resonance imaging (MRI) analysis of Atg7^+/+ and Atg7^Δ/Δ mouse prostates PC. (F) MRI-guided volume quantification of individual mice with Atg7^+/+ and Atg7^Δ/Δ anterior prostates at various times from 6 through 58 wk PC. (G) Kaplan-Meier survival curve of castrated mice with Atg7^+/+ and Atg7^Δ/Δ prostates over time.