Table 2.
Correlation of ZAP-70 analyses with IgHV mutational status as prognostic markers (n=343)
| Characteristics | Percentage method (cases)
|
Geo MFI index method (cases)
|
||||
|---|---|---|---|---|---|---|
| ≥20% | <20% | Conc (%) | <3.5 | ≥3.5 | Conc (%) | |
| M IgHV | 61 | 139 | 57.7 | 56 | 144 | 64.4 |
| UM IgHV | 59 | 84 | P=0.051 | 77 | 66 | P<0.001 |
Note: Statistically significant results are shown in bold.
Abbreviations: IgHV, immunoglobulin heavy chain variable; Geo MFI, geometric mean fluorescence intensity; M IgHV, mutated IgHV gene status; UM IgHV, unmutated IgHV gene status; % conc, overall percentage of concordance between the two prognostic parameters; ZAP-70, ζ-chain-associated protein kinase 70 kDa.