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Coagulation cascade depicting site of action of anticoagulants and reversal agents.
Notes: Dark gray: Idarucizumab – potential reversal agent for direct thrombin inhibitor (dabigatran). Light gray: Perosphere – potential reversal agents for drugs in dashed box. White: Andexanet alfa – potential reversal agent for drugs in solid box.
Abbreviation: LMWH, low molecular weight heparin.
