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. 2015 Oct 30;15(1):93–108. doi: 10.1074/mcp.M115.052332

Table I. Proteins differentially abundant between estrus and luteal phase in the cervical mucus. Proteins more abundant in oestrus and luteal phase: list of the 20 quantitatively main proteins based on spectral counting quantitative method at oestrus and luteal phase. Estrus: NSC (normalized spectral counts) at oestrus. Luteal phase: NSC during luteal phase. O/LP ratio: oestrus/luteal phase ratio of NSC.

Proteins name Gene symbol Estrus Luteal phase O/LP Ratio
More abundant in oestrus
    Serotransferrin TF 217.1 107.39 2.02
    Heat shock protein HSP 90-α HSP90AA1 165.9 9.37 17.71
    Complement C3 C3 109.2 65.56 1.67
    α-2-HS-glycoprotein AHSG 52.4 17.04 3.08
    α-2-macroglobulin A2M 46.1 3.65 12.64
    Glutathione S-transferase P GSTP1 38.3 17.25 2.22
    Mucin-5B MUC5B 37.6 8.41 4.47
    Glutathione S-transferase Mu 1 GSTM1 31.4 4.86 6.45
    Apolipoprotein A-I APOA1 31.1 6.31 4.92
    Triosephosphate isomerase TPI1 24.0 6.32 3.80
    Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 23.5 6.72 3.50
    Fibronectin FN1 21.9 5.77 3.80
    Elongation factor 1-α1 EEF1A1 21.5 8.42 2.55
    Elongation factor 2 EEF2 19.8 1.09 18.19
    14–3-3 protein epsilon YWHAE 19.0 5.33 3.57
    14–3-3 protein zeta/delta YWHAZ 18.0 6.96 2.58
    α-1B-glycoprotein A1BG 16.5 3.65 4.52
    α-enolase ENO1 15.8 3.59 4.40
    Heat shock protein β-1 HSPB1 15.4 6.02 2.56
    Chloride intracellular channel protein 1 CLIC1 14.5 5.04 2.87
More abundant in luteal phase
    Lactotransferrin LTF 273.8 937.0 0.29
    Ceruloplasmin CP 129.6 278.6 0.47
    Alkaline phosphatase ALPL 15.8 80.1 0.20
    Deleted in malignant brain tumors 1 protein DMBT1 14.8 65.3 0.23
    EGF-containing fibulin-like extracellular matrix protein 1 EFEMP1 0.0 63.5 0.00
    Polymeric immunoglobulin receptor PIGR 4.6 22.3 0.21
    Galectin-3-binding protein LGALS3BP 0.0 22.2 0.00
    CD9 antigen CD9 0.0 17.3 0.00
    Histone H4 HIST1H4H 1.8 13.0 0.14
    Inhibitor of carbonic anhydrase ICA 5.0 11.4 0.44
    Aminopeptidase N ANPEP 0.6 9.6 0.06
    N-acetylglucosamine-6-sulfatase GNS 0.0 7.2 0.00
    Zinc-alpha-2-glycoprotein AZGP1 0.0 6.3 0.00
    Tissue alpha-l-fucosidase FUCA1 0.0 5.4 0.00
    Angiotensin-converting enzyme ACE 0.0 5.2 0.00
    β-hexosaminidase subunit alpha HEXA 0.0 5.0 0.00
    Complement factor I CFI 0.3 3.7 0.09
    Pancreatic secretory granule membrane major glycoprotein GP2 GP2 0.0 3.6 0.00
    Factor XIIa inhibitor SERPING1 0.3 3.2 0.09
    Aldehyde dehydrogenase family 3 member B1 ALDH3B1 0.0 2.5 0.00