Table 2.
Initial post-transplant medication
| Parameter | Long-term use of amiodarone prior to HTX (n=74) | No long-term use of amiodarone prior to HTX (n=456) | P-value |
|---|---|---|---|
| Cyclosporine A, n (%) | 43 (58.1) | 297 (65.1) | 0.2426 |
| Tacrolimus, n (%) | 31 (41.9) | 159 (34.9) | 0.2426 |
| Azathioprine, n (%) | 36 (48.6) | 231 (50.7) | 0.7485 |
| Mycophenolate mofetil, n (%) | 38 (51.4) | 225 (49.3) | 0.7485 |
| Steroids, n (%) | 74 (100.0) | 456 (100.0) | na |
| Acetylsalicylic acid, n (%) | 7 (9.5) | 34 (7.5) | 0.5496 |
| Beta-blocker, n (%) | 7 (9.5) | 72 (15.8) | 0.1561 |
| Ivabradine, n (%) | 3 (4.1) | 27 (5.9) | 0.5191 |
| Calcium channel blocker, n (%) | 15 (20.3) | 114 (25.0) | 0.3792 |
| Dihydropyridine, n (%) | 4 (5.4) | 47 (10.3) | 0.1848 |
| Non-dihydropyridine, n (%) | 11 (14.9) | 67 (14.7) | 0.9691 |
| ACE inhibitor/sartan, n (%) | 29 (39.2) | 211 (46.3) | 0.2562 |
| Diuretic, n (%) | 74 (100.0) | 456 (100.0) | na |
| Statin, n (%) | 28 (37.8) | 162 (35.5) | 0.7005 |
| Gastric protection, n (%) (PPI/H2 blocker) | 74 (100.0) | 456 (100.0) | na |
Abbreviations: HTX, heart transplantation; ACE inhibitor, angiotensin-converting-enzyme inhibitor; PPI, proton pump inhibitor; H2 blocker, histamine receptor blocker; n, number; na, not applicable.