Table 5.
Effect of different multicomponent self-management intervention compared to usual care on HRQoL
| Intervention | Follow-up at ≤3 months
|
Follow-up at >3 to ≤6 months
|
Follow-up at >6 months
|
||||||
|---|---|---|---|---|---|---|---|---|---|
| Number of studies (participants) | Summary MD (95% CIs) | I2 (%) | Number of studies (participants) | Summary MD (95% CIs) | I2 (%) | Number of studies (participants) | Summary MD (95% CIs) | I2 (%) | |
| Multicomponent | |||||||||
| SGRQ | 18 (1,296) | 6.50 (3.62–9.39)* | 82.4 | 14a (1,905) | 4.47 (1.93–7.02)* | 79.6 | 16 (2,816) | 2.40 (0.75–4.04)* | 57.9 |
| CRQ | 7 (430) | 0.40 (0.01–0.79)* | 75.7 | 5 (360) | 1.02 (0.05–1.98)* | 93.2 | 3 (272) | 1.21 (−0.47 to 2.88) | 96.2 |
| Multicomponent with supervised exercise | |||||||||
| SGRQ | 14 (841) | 7.75 (3.49–12.01)* | 80.1 | 6 (580) | 6.57 (3.24–9.90)* | 77.6 | 4 (251) | 1.13 (−2.81 to 5.08) | 0.0 |
| CRQ | 7 (416) | 0.43 (0.03–0.83)* | 77.8 | 6 (380) | 1.02 (0.19–1.86)* | 92.0 | 3 (272) | 1.21 (−0.47 to 2.88) | 95.2 |
| Multicomponent with structured, unsupervised exercise | |||||||||
| SGRQ | – | – | – | – | 3.59 (1.28 to 5.91)* | 0.0 | 5 (776) | 0.80 (−1.03 to 2.63) | 2.3 |
| CRQ | 1 (34) | 0.61 (−0.18 to 1.41) | n/a | 4 (714) | – | – | – | – | – |
| Multicomponent with exercise counseling only | |||||||||
| SGRQ | 1 (177) | 1.32 (−2.97 to 5.61) | n/a | 3 (305) | 1.87 (−4.43 to 8.18) | 71.2 | 4 (1,021) | 3.88 (−1.39 to 9.14) | 74.6 |
| CRQ | – | – | – | – | – | – | – | – | – |
| Multicomponent without exercise advice or support | |||||||||
| SGRQ | 3 (278) | 4.65 (−1.45 to 10.74) | 82.0 | 2 (218) | 2.75 (−3.24 to 8.74) | 0.0 | 3 (702) | 3.73 (−0.99 to 8.44) | 81.1 |
| CRQ | – | – | – | – | – | – | – | – | – |
Notes: Positive MD represents an improvement for SGRQ and CRQ.
*
P<0.05.
a
15 comparisons. – indicates no data.
Abbreviations: CIs, confidence interval; CRQ, chronic respiratory disease questionnaire; HRQoL, health-related quality of life; MD, mean difference; SGRQ, St George’s respiratory questionnaire; n/a, not applicable.