Table 4. RNA microarray analysis: differential expression of select genes in A549 cells treated with 6.

Gene ID	Gene symbol	Gene description	FC	P-value
79094	CHAC1	ChaC, cation transport regulator homolog 1	5.56	1.19205 × 10–7
1649	DDIT3	DNA-damage-inducible transcript 3	4.43	4.30297 × 10–9
57761	TRIB3	Tribbles pseudokinase 3 (TRIB3)	4.41	6.5417 × 10–8
440	ASNS	Asparagine synthetase (glutamine-hydrolyzing)	3.94	3.28201 × 10–8
27063	ANKRD1	Ankyrin repeat domain 1 (cardiac muscle)	3.90	0.000102275
9518	GDF15	growth differentiation factor 15	2.90	9.19533 × 10–6
7779	SLC30A1	Solute carrier family 30 (zinc transporter)	2.86	0.002992119
23645	PPP1R15A	Protein phosphatase 1, regulatory subunit 15A	2.79	7.03697 × 10–7
7436	VLDLR	Very low density lipoprotein receptor	2.56	3.7443 × 10–6
9709	HERPUD1	Homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain	2.48	2.53382 × 10–7
2081	ERN1	Endoplasmic reticulum to nucleus signaling 1	2.44	1.02427 × 10–6
3162	HMOX1	Heme oxygenase (decycling) 1	2.41	6.63288 × 10–5
4495	MT1G	Metallothionein 1G	2.24	0.034444693
467	ATF3	Activating transcription factor 3	2.10	1.231 × 10–6
16	AARS	Alanyl-tRNA synthetase	2.03	3.39778 × 10–6
2920	CXCL2	Chemokine (C-X-C motif) ligand 2	1.93	0.00014337
4490	MT1B	Metallothionein 1B	1.92	0.032952383
3576	CXCL8	Chemokine (C-X-C motif) ligand 8	1.92	1.10178 × 10–5
7494	XBP1	X-box binding protein 1	1.87	3.60972 × 10–5
4496	MT1H	Metallothionein 1H	1.77	0.025658976
3311	HSPA7	Heat shock 70 kDa protein 7	1.63	0.008645638
6782	HSPA13	Heat shock protein 70 kDa family, member 13	1.54	0.001471724
3309	HSPA5	Heat shock 70 kDa protein 5 (glucose-regulated protein, 78 kDa)	1.51	2.83009 × 10–5
29948	OSGIN1	Oxidative stress induced growth inhibitor 1	1.48	0.000144965
57181	SLC39A10	Solute carrier family 39 (zinc transporter), member 10	0.63	0.016893383
3306	HSPA2	Heat shock 70 kDa protein 2	0.56	1.49155 × 10–5
6347	CCL2	Chemokine (C-C motif)	0.39	1.53404 × 10–5