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. Author manuscript; available in PMC: 2016 Feb 22.
Published in final edited form as: Clin Res Infect Dis. 2015 Sep 3;2(2):1018.

Figure 5. RM003 is more virulent than WT GBS such as A909.

Figure 5

Six - eight week old C57BL6/J mice were intravenously injected with 5 X 107 CFU of WT GBS A909 or RM003 (n = 5/group). Kalpan Meier survival curve shows percent survival of mice after the infection. Note that only 20% of mice infected with RM003 survived the infection whereas only 80% of mice infected with A909 succumbed to the infection (p = 0.057, Log-rank test; p = 0.0477, Gehan –Breslow-Wilcoxon test). Performance of the animal experiment was approved by the Seattle Children's ResearchI nstitutional Animal Care and Use Committee (protocol #13311) and performed in strict accordance with the recommendations in the Guide for the Care and Use of Laboratory Animals (Eighth Edition).