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. 2016 Feb 22;11(2):e0149387. doi: 10.1371/journal.pone.0149387

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© 2016 Kryza et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 8 — (A) Immunostaining of nodular melanoma using anti-hMMP-9 murine monoclonal antibody ab58803. Radiolabeling of adjacent tissue sections of nodular melanoma with ¹¹¹In-F3B-DOTA (B), and ¹¹¹In-DOTA-control sequence (C). Comparison of the results obtained by radiolabeling with ¹¹¹In-DOTA-F3B and by immunostaining. The results of immunohistochemical images corresponded with area with high activity. (D) Immunostaining of nodular melanoma with ab58803 murin monoclonal antibody anti-human MMP-9. It’s possible to identify the primitive nodular melanoma and an intrahypodermic node (E) Merged Images. (F) Radiolabeling with ¹¹¹In-DOTA-F3B.