Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Feb 19;7:10717. doi: 10.1038/ncomms10717

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Bar plots show FDs by sex and ASD status of sex-DE genes (FD≥1.2 and P<0.05) that also belong to ASD-associated co-expression modules²⁴. (a) Module asdM16_V, which is significantly upregulated in ASD and enriched for genes involved in the inflammatory response and immune system functions, and (b) module asdM12_V, which is significantly downregulated in ASD and enriched for genes with neuronal and synaptic functions. (c) FDs of sex-DE genes (FD≥1.2, P<0.05, 374 genes) by sex and status. Best-fit line and its 95% confidence interval are shown. CTL, control from ASD expression study; F, female; M, male.