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. 2016 Feb 19;7:10759. doi: 10.1038/ncomms10759

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(a) Aβ protofibril (PF) levels in brain tissue obtained from tg-ArcSwe (n=13) and tg-Swe (n=4) mice of different ages; total Aβ40 (b) and Aβ42 (c) levels in brain and cerebellum from tg-ArcSwe and tg-Swe mice of different ages; Pearson's correlation analysis of brain/cerebellum PET ratio and brain/cerebellum concentration ratio of soluble Aβ protofibrils in tg-ArcSwe and tg-Swe mice (d) and of total Aβ40 (e) and Aβ42 (f) in tg-ArcSwe mice. Each symbol represents one animal previously subjected to PET scanning; the line and error bars (a–c) indicate group mean±s.d.