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. 2016 Feb 19;7:10759. doi: 10.1038/ncomms10759

Figure 7. Comparison of PET imaging with [11C]PIB- and 124I-labelled fusion protein in transgenic and WT mice.

Figure 7

PET images obtained during 60 min 72 h after injection of [124I]8D3-F(ab′)2-h158, or during 20 min, starting 40 min after injection of [11C]PIB. Transverse and sagittal views of one representative 18-month-old tg-ArcSwe (a), tg-Swe (b) and WT (c) mouse with the two radioligands. (d) PET image-based quantification of brain distribution of [11C]PIB relative to that in cerebellum for tg-ArcSwe, tg-Swe and WT mice in the different age groups (each symbol represents one animal). Representative PET images are shown in ac. Number of animals included in each group is shown in d.