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. 2016 Feb 19;7:10759. doi: 10.1038/ncomms10759

Table 1. Ex vivo brain concentration of [125I]8D3-F(ab′)2-h158 at 72 h post injection.

  % Injected activity dose per gram brain tissue
Kp (brain-to-blood concentration ratio)
Age (months) Tg-ArcSwe WT Tg-ArcSwe WT
4 0.03±0.01 0.02±0.01 0.10±0.01 0.09±0.02
12 0.07±0.03*** 0.02±0.00 0.28±0.08*** 0.09±0.02
>18 0.14±0.04*** 0.02±0.00 0.44±0.10*** 0.06±0.01

All values are means±s.d. ***P<0.001 comparison between tg-ArcSwe and WT mice by two-way analysis of variance followed by Bonferroni's post hoc test.