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. 2015 Sep 16;20:207–217. doi: 10.1007/s00784-015-1589-y

Table 3.

An overview of the scored parameters collected from the selected literature

Article Outcome parameter Comment
Timing and technique of premaxillary correction
 Grabowski et al. (2006) Orthopaedic and orthodontic treatment starting at an early age:
N = 18 Good results no osteotomy required.
Two patients with crossbite
Class III in three patients
 Liou et al. (2004) Orthopaedic and orthodontic treatment between 8 and 11 years:
N = 8 correction of the premaxilla using a distractor
Overbite reduction to 0.7 mm
 Cronin et al. (1957) Surgery during neonatal period Bad outcome for maxillary growth
 Bishara et al. (1972) Osteotomy during neonatal period, compared with no osteotomy: Early osteotomy has a bad outcome on maxillary growth
SNA significantly smaller in osteotomy group.
SNB negative
Concave soft tissue profile
 Heidbüchel et al. (1993) Orthodontics and osteotomy: After osteotomy, better inclination of maxillary incisors
N = 22 prior to surgery orthodontic intrusion of the premaxilla. After osteotomy, SNA decreased by 2.02
 Scott et al. (2007) Age 8–12 years, good results surgical correction of the premaxilla. Collagen membrane was used to close the nasal mucosal layer
 Koh et al. (2013) N = 51, 36 patients treated with bone grafting only.
N = 7 wide cleft, good premaxillary position. Treated with a distractor
N = 8 surgical repositioning of premaxilla.
 Brouns et al. (1980) N = 31 surgical repositioning of premaxilla
In the Angle class I and II groups, good occlusion
In the Angle class III group, good occlusion
In the class IV group, good occlusion
 Akita et al. (2006) N = 17 divided into two groups
N = 10 no premaxillary osteotomy
N = 7 premaxillary osteotomy
 Aburezq et al. (2006) N = 4 osteotomy combined with secondary alveolar bone grafting.
 Freihofer et al. (1991) N = 13 surgical repositioning of the premaxilla between 8 and 12 years
N = 8 preoperative orthodontics
N = 10 postoperative orthodontics
 Geraedts et al. (2007) N = 40 combination of pre-orthodontic treatment and repositioning of the premaxilla between 8 and 12 years
 Narayanan et al. (2006) Tertiary osteotomy in children in developing countries. Children were not operated on until the tertiary osteotomy
Stability of the position of the premaxilla and bone volume
 Scott et al. (2007) N = 15 iliac crest bone transplants, all successful
93.96 % bone volume preserved after 3 months
 Koh et al. (2013) In 96.1 % of patients, more than 50 % transplant bone volume was preserved
 Brouns et al. (Brouns & Egyedi, (1980) Of the Angle class I and II patients N = 17, N = 11, consolidation no premaxillary instability
Angle class III group N = 13, N = 11 good consolidation
N = 2 remaining unstable premaxilla
Class IV N = 1 group stable premaxilla
 Carlini et al. (2009) N = 50, 45 patients no mobility of the premaxilla.
 Akita et al. (2006) The amount of bone required to fill the cleft was significantly lower in the osteotomy group.
 Aburezq et al. (2006) N = 3 with good consolidation and more than 50 % bone volume left. After trauma
N = 1 unstable premaxilla
 Freihofer et al. (1991) N = 9 rib bone
N = 3 mandibular bone
N = 1 local bone
N = 12 premaxilla stable and more than 50 % of bone preserved
 Narayanan et al. (2006) Uninhibited growth up to time of surgery on the premaxilla.
Effects of surgery or orthodontic intervention on maxillary growth
 Cronin et al. (1957) Surgery during neonatal period with disastrous effect on growth
 Bishara et al. (1972) Surgery during neonatal period with bad effect on maxillary growth
 Geraedts et al. (2007) N = 27 acceptable profile at the end of follow-up
N = 13 hypoplastic midface for which a Le Fort I procedure was carried out
No significant differences between osteotomy and non-osteotomy groups
 Padwa et al. (1991) N = 24 comparing three groups, for the effect of age on midfacial growth at time of surgery. Youngest group 6 years old.
No delay in midfacial growth in any of the groups.
Complications reported in the literature
 Heidbüchel et al. (1993) Premaxillary necrosis in one patient (5 %)
 Scott et al. (2007) N = 15, three patients with wound dehiscence
 Brouns et al. (1980) In the class III group, 11 patients with residual fistula, no necrosis of the premaxilla
 Carlini et al. (2009) N = 50 successful premaxilla repositioning and bone grafting in 48 patients. Two patients with premaxillary necrosis.
 Aburezq et al. (2006) No necrosis of the premaxilla. One patient with residual fistula
 Freihofer et al. (1991) N = 1 necrosis of the bone transplants on both sides
 Geraedts et al. (2007) N = 1 recurrent oronasal fistula