Abstract
The sensitivity to eight tetracyclines of 100 strains of brucellae, comprising strains of Brucella abortus, Br. melitensis, and Br. suis, was determined. Demethylchlortetracycline was the most effecitve against all the groups of brucellae, whereas oxytetracycline and chlortetracycline were the least effective. The mean MIC value for demethylchlortetracycline, doxycycline, lymecycline, and tetracycline was less than or equal to 1 mug/ml. Strains of Br. abortus biotype 2 and Br. suis were the most sensitive strains examined.
Full text
PDF



Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Giunchi G., De Rosa F., Fabiani F. Trimethoprim-sulfamethoxazole combination in the treatment of acute human brucellosis. Chemotherapy. 1971;16(5):332–335. doi: 10.1159/000220744. [DOI] [PubMed] [Google Scholar]
- Hassan A., Erian M. M., Farid Z., Hathout S. D., Sorensen K. Trimethoprim-sulphamethoxazole in acute brucellosis. Br Med J. 1971 Jul 17;3(5767):159–160. doi: 10.1136/bmj.3.5767.159. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kunin C. M. A guide to use of antibiotics in patients with renal disease. A table of recommended doses and factors governing serum levels. Ann Intern Med. 1967 Jul;67(1):151–158. doi: 10.7326/0003-4819-67-1-151. [DOI] [PubMed] [Google Scholar]
- Rizzo-Naudi J., Griscti-Soler N., Ganado W. Human brucellosis: an evaluation of antibiotics in the treatment of brucellosis. Postgrad Med J. 1967 Aug;43(502):520–526. doi: 10.1136/pgmj.43.502.520. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Robertson L., Farrell I. D., Hinchliffe P. M. The sensitivity of Brucella abortus to chemotherapeutic agents. J Med Microbiol. 1973 Nov;6(4):549–557. doi: 10.1099/00222615-6-4-549. [DOI] [PubMed] [Google Scholar]
- SPINK W. W. HOST-PARASITE RELATIONSHIP IN BRUCELLOSIS. Lancet. 1964 Jul 25;2(7352):161–164. doi: 10.1016/s0140-6736(64)90228-4. [DOI] [PubMed] [Google Scholar]
- Steigbigel N. H., Reed C. W., Finland M. Susceptibility of common pathogenic bacteria to seven tetracycline antibiotics in vitro. Am J Med Sci. 1968 Mar;255:179–195. doi: 10.1097/00000441-196803000-00005. [DOI] [PubMed] [Google Scholar]