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. 2016 Jan;71(1):17–21. doi: 10.6061/clinics/2016(01)04

Table 3.

Comparative analysis of the relationships between potential severe (contraindicated/severe) and non-severe (moderate/mild/none) interactions and other factors.

Factors Severe interactions Mean ± SD Non-severe interactions Mean ± SD p-value
Age (years) 80.89±7.6 79.6±8.5 0.35
Sex
    Female n (%) 83 (70.94) 41 (64.0) 0.34
Schooling 8.7±5.5 7.0±5.1 0.05
Comorbidity (Charlson index) 3.0±1.7 2.2±1.4 0.002
Number of drugs 7.68±2.6 3.8±2.2 <0.001
Executive function (DEX) 28.1±28.6 27.2±18.8 0.75
Dementia severity (MMSE) 18.6±5.9 15.7±6.8 0.005
Activities of daily living (Barthel index) 70.9±30.1 75.5±29.1 0.31
Instrumental activities (Lawton) 4.2±4.8 5.43±5.5 0.14
Caregiver burden (SCB 25-item) 25.3±18.6 20.0±14.0 0.03
Depression (NPI) (yes) n (%) 48 (75.0) 63 (53.85) 0.005

Pearson's Chi2 test was used for qualitative variables.

Student's t-test was used for quantitative variables.

Mini-Mental State Examination (MMSE), Screen for Caregiver Burden (SCB), Neuropsychiatric Inventory (NPI).