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. 2016 Jan;71(1):17–21. doi: 10.6061/clinics/2016(01)04

Table 4.

Factors associated with the presence of severe (contraindicated/severe) potential drug-drug interactions.

Variables OR CI (95%) p-value
Dementia severity (MMSE) total score 1.08 1.01-1.16 0.01
Comorbidity (Charlson index) total score 0.89 0.64-1.20 0.47
Number of medications 1.88 1.53-2.32 <0.001
Caregiver burden (SCB) total score 1.03 1.00-1.06 0.01
Depression (NPI) (yes) 3.19 1.24-8.20 0.01

Log likelihood=-70.819097, Pseudo R2=0.3977, Prob.>chi2=0.0000

Mini-Mental State Examination (MMSE), Screen for Caregiver Burden (SCB), Neuropsychiatric Inventory (NPI)