Table 3. Paired-samples t-test results for individual rs386770867 heterozygous samples.
| Sample | N | n | Mean cDNA AT:G | Diff of means (cDNA–gDNA) | 95% CI diff | Lower | Upper | Sig. | Overexpressed allele | Fold change |
|---|---|---|---|---|---|---|---|---|---|---|
| 8016_4 | 8 | 7 | 2.7290 | 0.9447 | 0.2841 | 0.661 | 1.229 | 0.001 | AT | 1.5295 |
| 8036_3 | 8 | 8 | 2.2489 | 0.4645 | 0.1243 | 0.340 | 0.589 | 0.0002 | AT | 1.2603 |
| 8036_4 | 8 | 8 | 2.3455 | 0.5612 | 0.6067 | −0.046 | 1.168 | 0.1127 | N/A | 1.3145 |
| 8046_4 | 8 | 8 | 2.0783 | 0.2940 | 0.1860 | 0.108 | 0.480 | 0.0174 | AT | 1.1648 |
| 8052_4 | 8 | 7 | 2.2372 | 0.4528 | 0.0483 | 0.405 | 0.501 | 1.677E−06 | AT | 1.2538 |
| 8060_5 | 8 | 8 | 2.0232 | 0.2389 | 0.0579 | 0.181 | 0.297 | 8.481E−05 | AT | 1.1339 |
| 8062_4 | 8 | 8 | 1.9644 | 0.1801 | 0.1141 | 0.066 | 0.294 | 0.017 | AT | 1.1009 |
| 8067_3 | 8 | 8 | 1.5871 | −0.1973 | 0.1887 | −0.386 | −0.009 | 0.091 | N/A | 0.8895 |
| 8080_3 | 8 | 8 | 2.5434 | 0.7590 | 0.1593 | 0.600 | 0.918 | 3.347E−05 | AT | 1.4254 |
| 8080_5 | 8 | 8 | 2.1789 | 0.3946 | 0.0975 | 0.297 | 0.492 | 9.641E−05 | AT | 1.2212 |
| 8081_4 | 8 | 8 | 2.2138 | 0.4295 | 0.1887 | 0.241 | 0.618 | 0.003 | AT | 1.2407 |
| 8100_3 | 8 | 8 | 1.9241 | 0.1398 | 0.1342 | 0.006 | 0.274 | 0.080 | N/A | 1.0784 |
| 8103_4 | 8 | 6 | 0.6981 | −1.0862 | 0.0220 | −1.108 | −1.064 | 2.228E−09 | G | 0.3912 |
| 8110_4 | 8 | 8 | 2.0563 | 0.2720 | 0.1438 | 0.128 | 0.416 | 0.0076 | AT | 1.1525 |
| 8111_5 | 8 | 7 | 2.1026 | 0.3183 | 0.0708 | 0.247 | 0.389 | 0.0001 | AT | 1.1784 |
| 8122_4 | 8 | 8 | 1.9307 | 0.1464 | 0.1292 | 0.017 | 0.276 | 0.0618 | N/A | 1.0820 |
| 8127_3 | 8 | 8 | 2.0927 | 0.3084 | 0.1382 | 0.170 | 0.447 | 0.0033 | AT | 1.1729 |
| 8135_3 | 8 | 8 | 1.9250 | 0.1407 | 0.2013 | −0.061 | 0.342 | 0.2131 | N/A | 1.0788 |
| 8135_4 | 8 | 7 | 1.7092 | −0.0751 | 0.1454 | −0.220 | 0.070 | 0.3502 | N/A | 0.9579 |
| 8136_3 | 8 | 8 | 2.2603 | 0.4760 | 0.1183 | 0.358 | 0.594 | 9.988E−05 | AT | 1.2667 |
| 8146_3 | 8 | 8 | 1.8690 | 0.0847 | 0.1456 | −0.061 | 0.230 | 0.2916174 | N/A | 1.0475 |
| 8146_4 | 8 | 8 | 2.1852 | 0.4009 | 0.1167 | 0.284 | 0.518 | 0.0003 | AT | 1.2247 |
| 8148_4 | 8 | 8 | 1.9540 | 0.1697 | 0.1202 | 0.050 | 0.290 | 0.0278 | AT | 1.0951 |
| 8148_5 | 8 | 8 | 1.9686 | 0.1843 | 0.0895 | 0.095 | 0.274 | 0.0049 | AT | 1.1033 |
| 8154_3 | 8 | 8 | 2.0219 | 0.2376 | 0.1158 | 0.122 | 0.353 | 0.0050 | AT | 1.1331 |
| 8158_4 | 8 | 8 | 1.8610 | 0.0767 | 0.0561 | 0.021 | 0.133 | 0.0315 | AT | 1.0430 |
| 8176_5 | 8 | 7 | 1.8324 | 0.0481 | 1.0002 | −0.952 | 1.048 | 0.9280 | N/A | 1.0269 |
| 8187_3 | 8 | 8 | 1.8010 | 0.0167 | 0.0660 | −0.049 | 0.083 | 0.6349 | N/A | 1.0094 |
| 8187_4 | 8 | 8 | 1.9886 | 0.2043 | 0.1132 | 0.091 | 0.318 | 0.0095 | AT | 1.1145 |
| 8189_3 | 8 | 8 | 2.0520 | 0.2677 | 0.1564 | 0.111 | 0.424 | 0.0122 | AT | 1.1500 |
| 8199_3 | 8 | 8 | 2.4459 | 0.6616 | 0.2383 | 0.423 | 0.900 | 0.0010 | AT | 1.3708 |
| 8199_4 | 8 | 8 | 2.4312 | 0.6469 | 0.1697 | 0.477 | 0.817 | 0.0001 | AT | 1.3625 |
| 8199_5 | 8 | 8 | 2.5618 | 0.7775 | 0.0762 | 0.701 | 0.854 | 1.95E−07 | AT | 1.4357 |
| 8208_3 | 8 | 8 | 1.8682 | 0.0839 | 0.0907 | −0.007 | 0.175 | 0.113 | N/A | 1.0470 |
| 8208_4 | 8 | 8 | 2.4574 | 0.6731 | 0.3703 | 0.303 | 1.043 | 0.009 | AT | 1.3772 |
| Population | 280 | 273 | 2.0702 | 0.2859 | 0.0538 | 0.232 | 0.340 | 1.258E−21 | AT | 1.1602 |
| Population (edited) | 232 | 232 | 2.0979 | 0.3136 | 0.0446 | 0.269 | 0.358 | 5.656E−32 | AT | 1.1757 |
| Male | 152 | 149 | 2.1657 | 0.3814 | 0.0756 | 0.306 | 0.457 | 5.07E−18 | AT | 1.2137 |
| Male (edited) | 128 | 128 | 2.1492 | 0.3649 | 0.0650 | 0.300 | 0.430 | 3.409E−20 | AT | 1.2045 |
| Female | 128 | 124 | 1.9555 | 0.1712 | 0.0711 | 0.100 | 0.242 | 6.353E−06 | AT | 1.0960 |
| Female (edited) | 104 | 104 | 2.0348 | 0.2504 | 0.0571 | 0.193 | 0.307 | 9.278E−14 | AT | 1.1404 |
Abbreviations: CI, confidence interval; edited, only cDNA data from samples with no cDNA outliers used; gDNA, genomic DNA; mean gDNA AT:G ratio for population used=1.78431493189407; mean gDNA G:AT ratio for population used=0.567229238822408; n, number of replicate results excluding outliers based on lying outside 1.5x interquartile range; N, number of replicate results; N/A, not applicable; Sig., significance.
Significance based on paired-samples t-test.