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. 2016 Jan 27;103(3):794–800. doi: 10.3945/ajcn.115.121780

TABLE 3.

RRs (95% CIs) for the association between each 1-mmol/L increase in maternal fasting plasma glucose concentrations and offspring adiposity measures at birth and follow-up

Crude
Model 11
Model 1 + birth weight2
n RR (95% CI) P value RR (95% CI) P value RR (95% CI) P value
Macrosomia (birth weight >4000 g) 661 1.18 (1.05, 1.32) 0.006 1.21 (1.07, 1.38) 0.003 NA3 NA
Large-for-gestational age 661 1.18 (1.03, 1.34) 0.016 1.19 (1.02, 1.39) 0.026 NA NA
Overweight/obesity at 5 mo4 405 1.07 (0.77, 1.48) 0.697 1.18 (0.79, 1.78) 0.417 1.07 (0.70, 1.65) 0.755
Overweight/obesity at 12 mo4 397 1.04 (0.84, 1.28) 0.724 1.09 (0.84, 1.40) 0.514 1.03 (0.80, 1.33) 0.824
Overweight/obesity at 7 y5 351 1.27 (1.07, 1.51) 0.007 1.21 (1.01, 1.50) 0.041 1.20 (1.01, 1.49) 0.042
1

Adjusted for maternal age at index child's birth, parity, socioeconomic status, prepregnancy BMI, smoking during pregnancy, gestational age at oral-glucose-tolerance test, gestational weight gain, and gestational age at delivery. For multivariate analyses, the final sample sizes were 616, 381, 374, and 325 for ponderal index and BMI z scores at 5 mo, 12 mo, and 7 y, respectively, because of missing data on prepregnancy BMI, parity, and socioeconomic status.

2

Adjusted for covariates in model 1 and child’s birth weight.

3

NA, not applicable.

4

Defined as age- and sex-specific BMI-for-age z scores >85th percentile according to the WHO Child Growth Standards.

5

Defined as age- and sex-specific BMI-for-age z scores >2 SD according to the WHO growth reference.